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Viruses, Vol. 15, Pages 1925: Bridging the Gap: Can COVID-19 Research Help Combat African Swine Fever?
hanarat African swine fever (ASF) is a highly contagious and economically devastating disease affecting domestic pigs and wild boar, caused by African swine fever virus (ASFV). Despite being harmless to humans, ASF poses significant challenges to the swine industry, due to sudden losses and trade restrictions. The ongoing COVID-19 pandemic has spurred an unparalleled global research effort, yielding remarkable advancements across scientific disciplines. In this review, we explore the potential technological spillover from COVID-19 research into ASF. Specifically, we assess the applicability of the diagnostic tools, vac...
Source: Viruses - September 15, 2023 Category: Virology Authors: Danaya Pakotiprapha Sakonwan Kuhaudomlarp Ruchanok Tinikul Sittinan Chanarat Tags: Review Source Type: research

A useful tool for the safe diagnosis and control of the two main pandemics of the XXI century: COVID-19 and African Swine Fever disease
by Sandra Barroso-Ar évalo, Marta Díaz-Frutos, Aleksandra Kosowska, Marta Pérez-Sancho, Lucas Domínguez, José Manuel Sánchez-Vizcaíno The COVID-19 pandemic and the disease triggered by the African Swine Fever virus are currently two of the main problems regarding public and animal health, respectively. Although vaccination seems to be the ideal tool for controlling these diseases, it has several limitations. Therefore, early det ection of the pathogen is critical in order to apply preventive and control measures. Real-time PCR is the main technique used for the detection of both viruses, which requires previous pro...
Source: PLoS One - March 6, 2023 Category: Biomedical Science Authors: Sandra Barroso-Ar évalo Source Type: research

News at a glance: African swine fever vaccine, low-dose radiation, and bees as ‘fish’
Some content has been removed for formatting reasons. Please view the original article for the best reading experience. Table of contents A version of this story appeared in Science, Vol 376, Issue 6598. Download PDF AGRICULTURE Vaccine targets African swine fever Vietnam’s agriculture ministry last week gave limited authorization to a vaccine hailed as an important tool to control one of the most serious animal diseases, African swine fever (ASF). In recent years the sickness has hit pig herds hard in several Asian and European countries...
Source: Science of Aging Knowledge Environment - June 9, 2022 Category: Geriatrics Source Type: research

Measurement of airborne particle emission during surgical and percutaneous dilatational tracheostomy COVID-19 adapted procedures in a swine model: Experimental report and review of literature
ConclusionsCOVID-19 adaptations allow preventing for major aerosol leaks for both ST and PDT, contributing to preserving healthcare workers during COVID-19 outbreak, but failed to achieve a perfectly airtight procedure. However, with COVID-19 adaptations, PDT required more expiratory pauses and more time than ST. Human factors and adverse events may lead to aerosolization and might be more frequent in PDT.
Source: PLoS One - November 23, 2022 Category: Biomedical Science Authors: Valentin Favier Source Type: research

Threads Blocks Search Results For ' COVID ' And ' Vaccines ' , Upsetting Users
Threads Blocks Search Results For 'COVID' And 'Vaccines', Upsetting Users Authored by Bryan Jung via The Epoch Times, Threads, Meta's recent competitor to Twitter, is facing harsh criticism for blocking search results for terms related to the pandemic, including vaccines. The new text platform,…#bryanjung #epochtimes #threads #meta #twitter #threadsusersshocked #michaelrobertson #xmeta #misinfo #namesotherplatforms
Source: Reuters: Health - September 14, 2023 Category: Consumer Health News Source Type: news

New Research Provides Hope In The Search For A Respiratory Syncytial Virus Vaccine- Part III
While the search for a vaccine for respiratory syncytial virus has eluded scientists and vaccine manufacturers for decades, it looks as if there may be a vaccine in the foreseeable future, within the next few years.
Source: Forbes.com Healthcare News - May 10, 2022 Category: Pharmaceuticals Authors: William A. Haseltine, Contributor Tags: Healthcare /healthcare Innovation /innovation Coronavirus business pharma & Source Type: news

Viruses, Vol. 15, Pages 1065: Intra-Host Co-Existing Strains of SARS-CoV-2 Reference Genome Uncovered by Exhaustive Computational Search
In this study, we present a computational method aimed at identifying co-existing intra-host strains of the virus from RNA-sequencing data of short reads that were used to assemble the original reference genome. Our method consisted of five key steps: extraction of relevant reads, error correction for the reads, identification of within-host diversity, phylogenetic study, and protein binding affinity analysis. Our study revealed that multiple strains of SARS-CoV-2 can coexist in both the viral sample used to produce the reference sequence and a wastewater sample from California. Additionally, our workflow demonstrated its ...
Source: Viruses - April 26, 2023 Category: Virology Authors: Xinhui Cai Tian Lan Pengyao Ping Brian Oliver Jinyan Li Tags: Article Source Type: research

Hyperimmune immunoglobulin for people with COVID-19
CONCLUSIONS: We included data from five RCTs that evaluated hIVIG compared to standard therapy, with participants with moderate-to-severe disease. As the studies evaluated different preparations (from humans or from various animals) and doses, we could not pool them. hIVIG prepared from humans may have little to no impact on mortality, and clinical improvement and worsening. hIVIG may increase grade 3-4 adverse events. Studies did not evaluate quality of life. RBD-specific polyclonal F(ab´)2 fragments of equine antibodies may reduce mortality and serious adverse events, and may reduce clinical worsening. However, the stud...
Source: Cochrane Database of Systematic Reviews - January 26, 2023 Category: General Medicine Authors: Catherine Kimber Sarah J Valk Khai Li Chai Vanessa Piechotta Claire Iannizzi Ina Monsef Erica M Wood Abigail A Lamikanra David J Roberts Zoe McQuilten Cynthia So-Osman Lise J Estcourt Nicole Skoetz Source Type: research

He battled AIDS, COVID-19, and Trump. Now, Anthony Fauci is stepping down
Anthony Fauci, the renowned physician-scientist who has led the $6.3 billion National Institute of Allergy and Infectious Diseases (NIAID) for nearly 4 decades and since early 2020 has been the U.S. government’s voice of scientific reason during the COVID-19 pandemic, will step down from government service in December. Fauci, 81, had said in recent interviews that he planned to retire from the government by the end of President Joe Biden’s administration, but did not give a date until today. He said in a statement that although leading NIAID “has been the honor of a lifetime,” he plans to “pursue...
Source: Science of Aging Knowledge Environment - August 22, 2022 Category: Geriatrics Source Type: research

Expression and immunogenicity of recombinant porcine epidemic diarrhea virus Nsp9
In this study, PEDV Nsp9 protein fused with MBP protein and His-tag were expressed and purified in Escherichia coli. Furthermore, immunization of MBP-Nsp9 enhances both humoral and cellular immunity responses as compared with that of His-Nsp9 protein. Finally, the swine immunization showed that Nsp9 protein could stimulate the swine immunity system to carry out humoral immunity, and the generated antibody could inhibit the proliferation of PEDV in Vero cells. Altogether, our data provide direct evidence for the immunogenicity of PEDV Nsp9, which sheds light on the future developments of anti-PEDV drugs and vaccines for PED...
Source: Virology - August 12, 2023 Category: Virology Authors: Shiguo Liu Qijia Yu Sha Li Mingzhi Li Li Yang Quansheng Wang Zewen Tu Feifei Tao Pingping Yang Lingbao Kong Xiu Xin Source Type: research

Utilizing Google trends to monitor coronavirus vaccine interest and hesitancies
CONCLUSION: Misinformation RSVs were highest after FDA authorization and have multiple repeated spikes after subsequent vaccine announcements. General information seeking terms peaked concurrently with increased vaccination uptake in the United States. Search interest has decreased with wider vaccine availability, despite many individuals in the United States remaining unvaccinated. GT can be used to monitor trends in public attitudes and misinformation regarding COVID-19 vaccines and further target education.PMID:35660035 | PMC:PMC9149202 | DOI:10.1016/j.vaccine.2022.05.070
Source: Vaccine - June 6, 2022 Category: Allergy & Immunology Authors: Emily Merrick Joshua P Weissman Sameer J Patel Source Type: research